THE STRATEGY
One mechanism can never be enough to address the complexity of ageing.
Our approach is to rescue damaged, aging cells, rather than execute them.
We trust measurable results over theoretical concepts.
WHAT IS MUSE 28?
REINFORCING CELL MEMBRANES
Astaxanthin has been observed to stabilize the lipid bilayer.
When the lipid bilayer is compromised, the parts of the cell that are supposed to be inside start to spill outside. This causes a cascade of warning alarms that disrupt nearby neighboring cells.
ENHANCING OSMOLYTE STABILITY
Betaine helps mosturize skin.
When there is too much water outside the cell, it creates hypoosmotic stress. The cells begin to swell as water floods through the cell membrane. When there is too little water, that is called hypertonic stress. Water rushes out of the cell and it shrivels up. Betaine has been observed to help maintain a balanced, isotonic environment.
REDUCING OXIDATIVE STRESS
Astaxanthin is 6000 times stronger than Vitamin C in combating oxidative stress.
When fruit is left exposed to oxygen, they visibly change due to the shifting of electrons from oxidation. Your cells are no different.
IGNITING METABOLOMICS
Alpha-ketoglutarate is a key component of the Krebs Cycle, which may explain how it assists biological age reversal.
As we age, it becomes harder for our cells to use energy properly. Adding fuel to power the furnace of our mitochondria makes sense from a basic standpoint. Scientists are still exploring why adding certain components of the Krebs Cycle have a more profound effect on biological age than others. Although more research needs to be done, there seems to be a general consensus that Alpha- ketoglutarate is the mitochondrial fuel with the most potent anti-aging effects.
.png)
OPTIMIZING GENE EXPRESSION
Alpha-ketoglutarate and glycine have been observed to enhance longevity.
Thousands of genes are implicated in the process of ageing. Many genes are interconnected. Elevating one gene will either raise or lower another. These complex webs are difficult to untangle, and only through observation of the final impact on healthspan and lifespan can we begin to grasp the importance of individual genes.
COMFORTING THE MICROBIOME
A pH of about 4 to 5 is optimal for beneficial bacteria.
At a pH near tomato juice, Muse 28 supports a healthy skin microbiome. If you have been using other skincare products, be sure to check them with a pH test strip. It should be slightly acidic.
SUPPLEMENTING MINERALS AND NUTRIENTS
More is not always better in biology.
We aim to supplement common vitamin and mineral deficiencies, with daily use in mind. We only add what is necessary. When too much of a particular vitamin or mineral is applied, the resulting imbalances can have negative consequences.
.png)
REFERENCES
-
Kidd, P., 2011. Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential. Altern Med Rev, 16(4), pp.355-364.
2. Stasiulewicz, M., Panuszko, A., Bruździak, P. and Stangret, J., 2022. Mechanism of Osmolyte Stabilization–Destabilization of Proteins: Experimental Evidence. The Journal of Physical Chemistry B, 126(16), pp.2990-2999.
3. Fassett, R.G. and Coombes, J.S., 2012. Astaxanthin in cardiovascular health and disease. Molecules, 17(2), pp.2030-2048.
4. Naeini, S.H., Mavaddatiyan, L., Kalkhoran, Z.R., Taherkhani, S. and Talkhabi, M., 2023. Alpha-ketoglutarate as a potent regulator for lifespan and healthspan: Evidences and perspectives. Experimental Gerontology, 175, p.112154.
5. Johnson, A.A. and Cuellar, T.L., 2023. Glycine and aging: Evidence and mechanisms. Ageing research reviews, p.101922.
6. Lambers, H., Piessens, S., Bloem, A., Pronk, H. and Finkel, P., 2006. Natural skin surface pH is on average below 5, which is beneficial for its resident flora. International journal of cosmetic science, 28(5), pp.359-370.
7. Roop, J.K., 2018. Hypervitaminosis-an emerging pathological condition. Int J Heal Sci Res, 8, p.280.